2. Selection, construction and practical implementation of experimental design tests
ToolAmong the plethora of experimental designs available, the Plackett-Burman (PB) design (Tool Validation of the robustness of an analytical method by Plackett-Burman design of experiments ) has gained widespread acceptance. This type of matrix has the advantage of involving a relatively small number of experiments compared with the total number of factors usually studied. For example, 11 variables can be studied in 12 experiments using a PB design (ASTM E1169-14).
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Selection, construction and practical implementation of experimental design tests
Experimental testing of the plan and collection of responses y
Bibliography
ISO 3534-3 Statistics - Vocabulary and symbols – Part 3: Experimental designs
ICH Q2 (R1): Validation of Analytical Procedures: Text and Methodology (2005)
W.J. Youden, Statistical Techniques for Collaborative Tests. Association of Official Analytical Chemists (AOAC), Washington, DC, USA (1967)
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