The essential consequences of polymorphism in the pharmaceutical field
Polymorphism. Basic principles and characterization methods

Most drugs are still prescribed orally in solid form (tablets, capsules, suspensions). Once in the stomach, the galenic form undergoes a disintegration process, gradually releasing the active ingredient throughout the gastrointestinal tract. The active ingredient then passes into solution in a molecular state. It can then diffuse towards the intestinal cell wall. Through a process of permeation, the active molecule passes through the cellular system into the bloodstream, where it can reach its site(s) of action (figure 1...