3. Interactions with blood compounds and regulatory requirements
The qualitative analysis of serum proteins that associate with particle surfaces has been the subject of numerous studies. Both quantitatively and qualitatively, the richness of nanoparticle-associated proteins results from the large surface area of nanoparticles, as well as from the nature of the surface, its hydrophobicity/hydrophilicity and its chemical composition.
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Interactions with blood compounds and regulatory requirements