5. Hydrodynamics and material transfer in cytocultivators
5.1 Hydrodynamics
The hydrodynamics of cytocultivators are broadly similar to those of gas-liquid stirred reactors, but with "gentle" stirring and aeration conditions. Agitation should ensure proper suspension of cells or microcarriers, homogenization of the liquid phase to limit any concentration gradients, reduced mixing times and increased material transfer capacities (O 2 and nutrients). However, as animal cells are reputed to be fragile,...
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Hydrodynamics and material transfer in cytocultivators
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