Conclusion
Multicomponent reactions and radical chemistry

Multicomponent reactions already have a long history and are proving highly useful for molecular diversity-oriented synthesis, offering rapid access to a wide variety of targets, particularly of biological interest. In this context, cascade radical processes occupy a privileged position and have yet to reveal their full potential. Radical reactions are generally carried out under mild conditions, compatible with a large number of functional groups and, for the most part, do not require protective groups. What's more, the orthogonality of reaction conditions for radical and ionic reactions means that substrates generated by multicomponent reactions can be functionalized sequentially, without purification of intermediates. The advent of sequential multicomponent processes thus opens up a wider field of investigation, giving access to complex polyfunctional substrates while minimizing the number...