2. Reactivity in water
Pericyclic reactions are reactions whose atomic utilization is total, making them particularly suitable for "green" syntheses.
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2.1.1 Diels-Alder and hetero Diels-Alder reactions
As mentioned above, the study of the Diels-Alder reaction
played a major role in developing the use of water as a solvent in synthesis. In fact, Diels and Alder had carried out the cycloaddition of furan and maleic anhydride in water as early as 1931. A few cases of cycloadditions...
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Reactivity in water
Bibliography
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LINDSTROM (U.M.) -
Organic reactions in water. Principles, strategies and applications
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Édité par Blackwell, 405 p. (2007).
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LI (C.-J.), CHAN (T.-H.) -
Comprehensive organic reactions in aqueous media
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