6. Outlook and developments
When it was first discovered in the early 1960s, redox isomerization was a laboratory curiosity, carried out under drastic conditions that were hardly compatible with functionalized substrates. Today, with the development of organometallic chemistry, it has become a reaction compatible with many substrates, and is used industrially for menthol synthesis. It is also associated with various processes via
tandem, sequential reactions (aldolization, alkylation, fluorination, etc.). Other tandem reactions, such as tandem redox isomerization/reductive amination
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Outlook and developments