Conclusion
Silk nanofibers-based biomaterials for biomedical applications

For many biomedical applications, the materials used must meet criteria such as ease of manufacture, biodegradability, biocompatibility, good mechanical resistance and often allow the circulation and exchange of molecules. The fibroin produced by Bombyx mori, which is of natural origin, meets all these conditions and can be chemically modified, has attracted growing interest from the scientific community. What's more, compared with solid three-dimensional matrices, microporous fibrous matrices with a high surface-to-volume ratio are often sought after for tissue engineering applications, where cell adhesion and proliferation are paramount. This is why the possibility of producing silk fibers of controlled diameter and orientation by electrospinning has further expanded the biomedical applications of this protein. However, despite fibroin's formidable properties, which make it particularly...