Glass transition
Amorphous and glassy states of molecular and pharmaceutical compounds: general properties

Figure 13 shows the evolution of the specific heat C _p of indomethacin during melting by heating a crystal and during supercooling, by cooling the liquid. The increase in C _p after melting (at T _m ) is associated with the dynamic release of the large-amplitude molecular degrees of freedom that characterize the liquid state. By cooling the liquid quickly enough (at a rate of around 10°C/min) below T _m , crystallization can...