1. From bone to bioactive ceramics
From a materials science perspective, vertebrate bones can be defined as mineral-organic nanocomposites with an elaborate, controlled architecture. The organic matrix consists of type I collagen molecules, organized in a triple helix 1.2 nm in diameter and 300 nm in length, resulting from extracellular self-assembly. These molecules form fibrils with a particular organization, leaving gaps between successive molecules (figure 1a )
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From bone to bioactive ceramics
Bibliography
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(1) - HODGE (A.J.) - Molecular models illustrating the possible distribution of holes in simple systematically staggered arrays of type I collagen molecules in native-type fibrils. - Connective Tissue Research, 21, p. 137-147 (1989).
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(2) - LANDIS (W.J.) - The strength...
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