Hydrodynamics and chromatographic efficiency
Centrifugal partition chromatography Operating conditions, modeling and scale-up

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J2787 V1 Article

Hydrodynamics and chromatographic efficiency
Centrifugal partition chromatography Operating conditions, modeling and scale-up

Authors : Luc MARCHAL, Jean-Hugues RENAULT, Sébastien CHOLLET

Publication date: March 10, 2017 | Lire en français

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2. Hydrodynamics and chromatographic efficiency

CPC is a chromatographic technique which, when implemented, is more akin to liquid-liquid extraction on a column (without trays or packing) [J 2 760] . Indeed, each partition cell can be likened to a small column whose stationary phase and mobile phase are the continuous phase and dispersed phase respectively.

The flow takes place in three stages (Figure 1 a ) :

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