Sample introduction
Organic Mass Spectrometry: Principle, introduction and ionization methods

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Sample introduction
Organic Mass Spectrometry: Principle, introduction and ionization methods

Author : David RONDEAU

Review date: September 2, 2020 | Lire en français

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2. Sample introduction

In mass spectrometry, analysis begins either with the direct introduction of the sample into the mass spectrometer source, or after a preliminary separation step of the mixture's constituents, usually performed by a chromatographic system. The introduction system chosen will depend on the physico-chemical properties of the sample constituents (thermal stability, polarity, solubility, size, etc.) and the operating characteristics of the source used.

2.1 Direct sample introduction

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