Chromatographic properties of carbon dioxide-based mobile phases
Supercritical Fluid Chromatography

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Chromatographic properties of carbon dioxide-based mobile phases
Supercritical Fluid Chromatography

Author : Didier THIÉBAUT

Review date: October 1, 2021 | Lire en français

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2. Chromatographic properties of carbon dioxide-based mobile phases

2.1 Thermodynamic aspect

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2.1.1 Influence of density

As in CPL, retention depends on solute-stationary phase, solute-supercritical fluid and supercritical fluid-stationary phase interactions. Solute-supercritical CO 2 interactions can be governed by varying its pressure and, hence, its density (figure 6 )

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