Conclusion
Processes of mass cultivation of animal cells

Industrial processes for culturing animal cells to produce therapeutic molecules are currently booming, particularly in the recombinant antibody and vaccine sectors. In addition to a strict regulatory framework, these processes are characterized by specific features such as nutritional requirements imposing a complex formulation of culture media, high cell sensitivity to their physico-chemical environment (pH, temperature, stress, etc.), and delicate operation. As a result, there is still considerable scope for improving their performance, notably through research into new cell lines, the use of better-controlled culture media, a better understanding of cell metabolism, the expert application of PAT methods or the fine modeling of transport phenomena in the bioreactor.