1. General presentation
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The search for new drugs has been greatly enriched by the contributions of combinatorial chemistry, high-throughput screening and molecular modeling. These tools, combined with advances in biology, have enabled the identification of original active principles, corresponding to lead compounds, whose optimization has led to the marketing of new drugs. However, the various drug targets have a protein, lipo- or glyco-protein structure,...
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General presentation
General
References
- (1) - - Ouvrages et revues traitant des rapports entre la stéréochimie et les propriétés pharmacologiques et pharmacocinétiques de médicaments : WINEFORDER (J.D.). – The impact of stereochemistry on drug development and use. Volume 12. John Wiley and Sons Inc., New York (1997) ; WAINER (I.W.) et DRAYER (D.E.). – Stereochemistry. Analytical methods and pharmacology....
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