2. Evolution of alloys used
The first materials used in medical applications were stainless steels and cobalt-chromium alloys. Despite their good resistance to corrosion, due to the formation of a passivation layer which renders them inert in a physiological environment, the release of metal ions is possible and is the cause of numerous harmful effects for the organism . What's more, their high elastic modulus compared with that of bone (190 GPa for stainless steels and 240 GPa for Co-Cr-based alloys)...
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Evolution of alloys used
Bibliography
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(1) - STEINEMANN (S.) - Corrosion of surgical implants-in vivo and in vitro tests, Evaluation of biomaterials. Advances in biomaterials. - John Wiley and Sons, p. 1-34 (1980).
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(2) - WOLFF (J.) - The law of bone remodeling [translated from the 1892 original] Das Gesetz...
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