Glossary
Industrial Toxicology

ADME (Absorption – Distribution – Metabolization – Excretion) :

Xenobiotic fate in the body.

Bioavailability; biodisponibility

Form, concentration and lifetime of a xenobiotic in the body.

Clastogenesis; clastogenesis

Chemical or physical action likely to cause breaks or deletions in a DNA molecule, creating a chromosomal aberration.

Concentration létale; lethal concentration

Concentration of a toxic substance that causes the death of a percentage of individuals in a given population, over a given period of time, when exposed to this toxic substance.

Demi-vie ;half life

Time required to eliminate half the amount of xenobiotic in the body.

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