Bacteriocins: production methods
Synthetic Biology applied on bacteriocins

Bacteriocins are naturally secreted by bacteria to control their environment. While the genetic nature of bacteriocins offers significant possibilities in terms of applications, this has long been a technological barrier to the domestication of these natural "objects".

Their production for application has come up against the inherent complexities of the biotechnology field, i.e. scale-up and standardization. Traditionally, these bacteriocins are produced from bacterial strains isolated from the environment or from industrial strains adapted in the laboratory, a process which requires an extensive optimization phase (figure 6 b). This phase includes not only production itself, but also purification. These two crucial stages can determine the economic viability of bacteriocins...