Influence of water and humidity on amorphous material
Amorphous and glassy states of molecular and pharmaceutical compounds Applications and uses

The physical and chemical properties of pharmaceutical solids are highly dependent on humidity. Water, or steam, is present at virtually every stage in the manufacture and storage of solid dosage forms. Variations in moisture content can lead to changes, whether desired or not, in many properties, such as flow, compaction, agglomeration, dissolution, hardness, etc., but also in subsequent stability . Crystalline and amorphous solids behave...