Chromatographic couplings with mass spectrometry. II : Quantitative analysis

Quantitative analysis
Chromatographic couplings with mass spectrometry. II

Author : Patrick ARPINO

Publication date: March 10, 2008 | Lire en français

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5. Quantitative analysis

From the outset, GC-MS has been perceived as a high-performance quantitative assay method [46] . Today, it is widely applied in pharmaceuticals for the determination of drugs and their metabolites, and in forensic science for the detection of fraud, counterfeiting, doping, etc.

5.1 Detection principles

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5.1.1 Electronic ionization detection

An EI-mode MS belongs to the category of chromatographic detectors delivering...

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Bibliography

References

n General works

l About mass spectrometry

(1) - TRALDI (P.), MAGNO (F.), LAVAGNINI (I.), SERAGLIA (R.) - Quantitative applications of mass spectrometry. - Wiley (2006).
(2) - GROSS (J.H.) - Mass Spectrometry : a textbook....

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Quantitative analysis Chromatographic couplings with mass spectrometry. II