2. Insufficient agronomic or pest control efficacy

From 1960 onwards, to overcome a number of unforeseen difficulties (resistance, persistence) that had become a cause for concern, knowledge of biochemical modes of action progressed and led to new requirements.

2.1 Resistance to fungicides

Dinocap (figure 7 a ), a decoupling agent specific to powdery mildew, was added to the range of fungicides in 1960. Dithianon (1963) (figure 7 b ) is a quinone with the same mode of action. Chlorothalonil (figure 7 c ) (TCPN), marketed in 1964, has preventive uses like its predecessors. It has very low mammalian...

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Insufficient agronomic or pest control efficacy