2. What are the links between genotoxicity and carcinogenesis?
Gene and/or chromosomal mutations can induce cancer, particularly when they affect certain "critical" genes: cell growth control genes, tumor suppressor genes, and genes that regulate cell death (apoptosis).
An oncogene is a gene whose expression promotes the development of cancer.
An anti-oncogene is a gene capable of inhibiting cell growth when introduced into tumor cells.
Any genotoxic agent is considered a potential carcinogen.
While most carcinogens are mutagenic, not all mutagens are carcinogenic (mutations on reproductive germ cells).
Exclusive to subscribers. 97% yet to be discovered!
Already subscribed? Log in!
What are the links between genotoxicity and carcinogenesis?
Is cancer inevitable?
Article included in this offer
"Chemical risk prevention manager"
(
218 articles
)
Updated and enriched with articles validated by our scientific committees
A set of exclusive tools to complement the resources
Bibliography
Also in our database
Exclusive to subscribers. 97% yet to be discovered!
Already subscribed? Log in!
