Synthesis of isonitriles
Isonitriles and multicomponent reactions
Article REF: CHV2200 V1
Synthesis of isonitriles
Isonitriles and multicomponent reactions

Authors : Laurent EL KAIM, Jieping ZHU

Publication date: May 10, 2010, Review date: October 25, 2017 | Lire en français

Logo Techniques de l'Ingenieur You do not have access to this resource.
Request your free trial access! Free trial

Already subscribed?

1. Synthesis of isonitriles

The first isonitrile was obtained by treating allyl bromide with silver cyanide (figure 1 ) [1]. This synthesis is virtually no longer used today, and isonitriles are mainly prepared by two methods: either directly from amines and chloroform in a basic medium (carbylamine reaction) or by dehydration of formamides.

.Synthesis by Lieke (1859)
You do not have access to this resource.
Logo Techniques de l'Ingenieur

Exclusive to subscribers. 97% yet to be discovered!

You do not have access to this resource. Click here to request your free trial access!

Already subscribed?

Article included in this offer

"Chemical risk prevention manager"

( 218 articles )

Complete knowledge base

Updated and enriched with articles validated by our scientific committees

Services

A set of exclusive tools to complement the resources

View offer details
Contact us
Contact our team FAQ