Selection, construction and practical implementation of experimental design tests

2. Selection, construction and practical implementation of experimental design tests

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Validation of the robustness of an analytical method by Plackett-Burman design of experiments

The roadmap defining all the experiments in the plan to be carried out is formalized in a table commonly referred to as the X experimental matrix.

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Selection, construction and practical implementation of experimental design tests

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ISO 3534-3 Statistics - Vocabulary and symbols – Part 3: Experimental designs
ICH Q2 (R1): Validation of Analytical Procedures: Text and Methodology (2005)
W.J. Youden, Statistical Techniques for Collaborative Tests. Association of Official Analytical Chemists (AOAC), Washington, DC, USA (1967)
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