4. Applications

4.1 DNA and RNA polynucleotides

DNA and RNA polynucleotides were the first objects to be studied by CDMS spectrometry. Indeed, as early as 1995-1997, Benner's group demonstrated the potential of CDMS for the analysis of polynucleotides of known molecular mass (between 2.8 and 31 MDa)

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Bibliography

(1) - ANTOINE (R.) - Weighing synthetic polymers of ultra-high molar mass and polymeric nanomaterials : what can we learn from charge detection mass spectrometry ?. - Rapid Communications in Mass Spectrometry, 34(S2), p. e8539 (2020).
(2) - KEIFER...

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