5. Protocols
The development of new estimation methods in MNLEMs and their implementation in software now facilitate the analysis of longitudinal pharmacological data. However, the choice of experimental protocol remains a fundamental and complex issue. In this section, we review the definition of an experimental protocol, then introduce the current methodology for evaluating and optimizing protocols. Finally, we describe the existing IT tools and use one of them to determine new protocols based on the example of warfarin data.
5.1 Sampling protocols
The population protocol Ξ is composed of the N so-called elementary protocols ξi (i = 1...N ) carried out in each of the study subjects. An elementary protocol ξi is defined by a number of samples ni and the times at which...
Exclusive to subscribers. 97% yet to be discovered!
Already subscribed? Log in!
Protocols
Conclusion and outlook
Bibliography
Exclusive to subscribers. 97% yet to be discovered!
Already subscribed? Log in!
Article included in this offer
"Drugs and pharmaceuticals"
(
131 articles
)
Updated and enriched with articles validated by our scientific committees
A set of exclusive tools to complement the resources
