Glossary
In vitro and in silico alternatives to animal models in toxicology

Environmental pollutants

Molecules present in the environment and not present in a given organism, liable to contaminate it through acute or chronic exposure.

Microenvironment

Environment of a cell or group of cells, itself composed of cells or matrix elements, interacting with these cells through physical (e.g. matrix) or secretory interactions of various kinds (hormones, growth factors, nutrients, etc.).

Organoid

Cell architecture that reproduces, in part under in vitro culture conditions, the complex properties of an organ or tissue.

Computational toxicology: the application of mathematics and computer models to :

• 1) to predict the adverse effects of substances ;

• ...