Frequently asked questions
Acute systemic toxicity: lethal doses LD50 and LC50, in vitro tests

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FIC1172 V1 Practical sheet

Frequently asked questions
Acute systemic toxicity: lethal doses LD50 and LC50, in vitro tests

Author : Alain LOMBARD

Publication date: May 10, 2025 | Lire en français

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6. Frequently asked questions

How is acute toxicity reflected in SDSs?

The type of study, LD50 or LC50 values, and clinical signs observed during the course of the studies must be indicated (see Toxicological data of an SDS: example of methylene chloride (Tool Picto outil 1 ), in which the various routes are indicated with regard to clinical signs and LC50 and LD50 values).

How to choose study protocols

The choice of study protocols depends on the intended use of the LD50 or LC50 values obtained.

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