1. What are DMELs?
Establishing DMELs is an important step in the overall process of assessing the hazards of a chemical substance. It is the logical follow-up to the studies carried out to determine the substance's ADME, and to the results of short-, medium- and long-term "in vitro and in vivo" toxicological studies.
1.1 Definition
Derived Minimal Effect Levels (DMELs) are the values to be defined under the European REACh regulation for chemicals whose effects on humans do not allow a threshold to be established.
These are reference values based on a relative risk of cancer, which are used to implement appropriate risk management measures for human populations, including workers.
A DMEL differs from a DNEL in that the substance's...
Exclusive to subscribers. 97% yet to be discovered!
Already subscribed? Log in!
What are DMELs?
How do I draw up a DMEL?
Bibliography
Also in our database
Exclusive to subscribers. 97% yet to be discovered!
Already subscribed? Log in!
Article included in this offer
"Safety and risk management"
(
477 articles
)
Updated and enriched with articles validated by our scientific committees
A set of exclusive tools to complement the resources
