How valid are test results?
Respiratory irritation, eye irritation, skin irritation: how does the localized action of chemical substances affect the body?

Irritation and corrosion tests must be carried out in accordance with international guidelines (OECD) and in laboratories working to Good Laboratory Practice (GLP/GLP) and using standardized procedures (SOP) (see Principles of Industrial and Regulatory Toxicology [FIC 1169] ).

The "in vivo" skin irritation test is performed on albino rabbits, whose skin is not colored and is thinner than that of humans. In addition, chemical substances are applied under a semi-occlusive dressing that keeps...