6. Catalytic Appel reaction
6.1 Introduction to Call Reaction
Another nucleophilic substitution reaction promoted by phosphines is the Appel reaction . In this transformation, alcohols (R3C-OH) are converted to alkyl halides (R3C-X), using a stoichiometric amount of triphenylphosphine. This reaction is commonly used in academic research and in industry since it allows the rapid creation of C-X bonds...
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Catalytic Appel reaction
Phosphine and asymmetric catalytic processes
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