1. Context
Organophosphorus compounds play a vital role in organic synthesis, and are used on a daily basis in academic laboratories and on a large scale in industry. Among the reactions promoted by phosphines are those of Wittig and aza-Wittig (formation of carbon-carbon and carbon-nitrogen double bonds), Mitsunobu (nucleophilic substitution on alcohol functions), Appel (alcohol halogenation reaction) or Staudinger (azide reduction to amine or amide formation reaction)
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