Practical sheet | REF: FIC1168 V1

ADME: circuit of a chemical substance in the body

Author: Alain LOMBARD

Publication date: February 10, 2025 | Lire en français

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6. Our advice

6.1 Find out more about the substance

  • If you have sufficient knowledge of the chemical's physico-chemical properties from the SDS, refer to the How can I assess the toxicity of a substance, based on its physico-chemical properties? [FIC 1167] sheet, and determine the potential for exposure in your industrial process. With the exception of medicines and plant protection products, you will rarely have data on the metabolism and half-life of a chemical substance in the body, but you may find data on its hydrolysis and stability, as well as its half-life in aquatic environments, or in accidental situations (e.g. hydrocyanic acetone, which hydrolyses to HCN in a few minutes)....

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