1. Acute toxicity
Acute toxicity is presented in Annex I of CLP part 3.1. It concerns three pathways:
ingestion: the chemical enters the body through the digestive tract;
inhalation: the chemical enters the body via the respiratory tract; the substance can be inhaled in various forms (vapors, aerosols, etc.);
cutaneous: the chemical enters the body through the skin.
Each route must be considered independently. A product may be toxic for one route and non-toxic for another.
For example, if you swallow viper venom, you risk nothing because the venom proteins are broken down in the stomach, whereas in the event of a bite, you need to act quickly.
This...
The Ultimate Scientific and Technical Reference
This article is included in
Safety and risk management
This offer includes:
Knowledge Base
Updated and enriched with articles validated by our scientific committees
Services
A set of exclusive tools to complement the resources
Practical Path
Operational and didactic, to guarantee the acquisition of transversal skills
Doc & Quiz
Interactive articles with quizzes, for constructive reading
Acute toxicity
Skin corrosion and irritation
Bibliography
Also in our database
Websites
You can find out more about CLP on the ECHA website (CLP section).
Please note: in the "Help for industry and authorities" section, you'll find various guides to implementing CLP.
Regulations
Règlement (CE) n°1272/2008 du 16 décembre 2008 CLP Regulation, on classification, labeling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No. 1907/2006.
The Ultimate Scientific and Technical Reference
