Practical sheet | REF: FIC1172 V1

Acute systemic toxicity: lethal doses LD50 and LC50, in vitro tests

Author: Alain LOMBARD

Publication date: May 10, 2025 | Lire en français

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4. Our advice

4.1 Make sure the test substance is batch-matched

You must ensure that the batch of substance tested is representative of your entire production, particularly in terms of concentration, purity and characterization of any impurities inherent in the production process. The experimental protocol chosen must be able to give you the information you need to classify and label the chemical substance, as well as to provide information on the real dangers in the event of accidental exposure of operators.

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4.2 Make sure the acute...

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