3. Direct line coupling, without splitter
The virtual disappearance of packed columns has rendered most molecular separators obsolete. Direct connection of a capillary column to a mass spectrometer is now the rule in all commercial GC-MS systems. However, even in the absence of a specific interfacing device, there are several ways of connecting a GC column directly to a mass spectrometer source, depending on the dimensions of the GC column, the vacuum pumping capabilities of the mass spectrometer, and the operating constraints specific to the laboratory (e.g. frequency of column exchange).
3.1 Sealed coupling
The coupling is tight when the end of the GC column is completely isolated from the laboratory atmosphere. There must be no air leakage at the point where the column is connected to the mass spectrometer,...
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Direct line coupling, without splitter
Sample preparation
Bibliography
References
n General works
l About mass spectrometry
Software
(non-exhaustive list)
AMDIS32 (Automated Mass Spectral Deconvolution & Identification System)
http://chemdata.nist.gov/mass-spc/amdis/
CODA (Component Detection Algorithm)
COMSPARI (Comparison of Spectral and Retention Information)
Databases, libraries
NIST05 (NIST/EPA/NIH Mass Spectral Library)
Wiley Registry of Mass Spectral Data
Accessory manufacturers
(non-exhaustive list)
PerkinElmer (Prevent kits, MS-Vent)
Restek (EZ No-Vent kit)
EMS (ms-Novent, ms-OpenSplit kits)
Reagent kit suppliers
(non-exhaustive list)
Carlo Erba
http://www.carloerbareagenti.com/
Pierce
Regis
...
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