4. Sample preparation
Samples brought into the laboratory are rarely ready for immediate GC-MS analysis, and sample preparation is a very important step in the analytical protocol.
4.1 Pre-treatment
As with GC, samples for GC-MS must be introduced into the injector in a solvent compatible with the column and injection modes (e.g., with or without flow splitting, with cold column injection, large volume injection, etc.), be free from solid particles that could block the injection needle, and be free from non-vaporizable compounds that could degrade or pollute the chromatographic column (see Gas chromatography
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Sample preparation
Quantitative analysis
Bibliography
References
n General works
l About mass spectrometry
Software
(non-exhaustive list)
AMDIS32 (Automated Mass Spectral Deconvolution & Identification System)
http://chemdata.nist.gov/mass-spc/amdis/
CODA (Component Detection Algorithm)
COMSPARI (Comparison of Spectral and Retention Information)
Databases, libraries
NIST05 (NIST/EPA/NIH Mass Spectral Library)
Wiley Registry of Mass Spectral Data
Accessory manufacturers
(non-exhaustive list)
PerkinElmer (Prevent kits, MS-Vent)
Restek (EZ No-Vent kit)
EMS (ms-Novent, ms-OpenSplit kits)
Reagent kit suppliers
(non-exhaustive list)
Carlo Erba
http://www.carloerbareagenti.com/
Pierce
Regis
...
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