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Article | REF: F3240 V1

Lyophilization

Authors: Michèle MARIN, Frédéric RENÉ

Publication date: March 10, 2000 | Lire en français

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    2. Industrial and development techniques

    Freeze-drying can be carried out using a variety of technologies. Sublimation can be carried out either by lowering the total pressure (vacuum freeze-drying), or by lowering the water vapor pressure in the direct vicinity of the product (freeze-drying with adsorbents at atmospheric pressure). The method for recovering the extracted water vapour then differs from case to case. A number of industrial techniques are also available to provide the heat required for dehydration.

    2.1 Vacuum freeze-drying

    A freeze-dryer typically comprises three components: a heating source, a steam trap and a vacuum pump. Generally speaking, the product to be freeze-dried is placed in trays. The trays are introduced into the freeze-drying chamber on superimposed rails. Two methods...

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