4. High-throughput sequencing — Tools and challenges for human health

Nathalie MARSAUD: Biology Engineer - GeT-Biochips Platform, LISBP, University of Toulouse, CNRS, INRA, INSA, Toulouse, France

Since the complete sequencing of the first human genome in 2003 using the Sanger method, high-throughput sequencing technologies, grouped together under the acronym NGS (Next Generation Sequencing), have continued to evolve. They are opening up new perspectives in both research and hospital settings. As a result, the traditional approach to medicine has evolved significantly, and is gradually moving towards a more personalized approach. The aim of human genome resequencing is to decipher the genetic make-up of each patient, in order to optimize the diagnosis and treatment of certain diseases. But the accessibility of human genome sequences...