2. Multi-component reactions and green chemistry

2.1 Saving steps

Conventional molecule synthesis routes create a single bond per step. This approach is very costly in terms of solvents, auxiliary reagents, energy and time. Multi-component reactions, on the other hand, create several bonds in a single operation in the same reaction medium, without purification of intermediates. They are therefore clean reactions in that the use of solvents is limited to the reaction itself. As intermediates are not isolated, purification steps, which consume large quantities of organic solvents, are limited, which also reduces the cost...