1. Multi-component reactions: principle and applications
1.1 Definition
Chemists now have at their disposal a large number of methods for developing new functionalized target molecules, on which depend future advances in the fields of medicine, biotechnology, crop protection and materials... Traditionally, over the last century, these molecules were essentially developed in successive steps, each of which allowed the incorporation of an additional fragment (component) making up the final structure. The structural and functional complexity sought is thus only accessible through a linear sequence of independent chemical transformations (figure 1 ).
The Ultimate Scientific and Technical Reference
This article is included in
Green chemistry
This offer includes:
Knowledge Base
Updated and enriched with articles validated by our scientific committees
Services
A set of exclusive tools to complement the resources
Practical Path
Operational and didactic, to guarantee the acquisition of transversal skills
Doc & Quiz
Interactive articles with quizzes, for constructive reading
Multi-component reactions: principle and applications
Multi-component reactions and green chemistry
Bibliography
Other works
ISAMBERT (N.) and LAVILLA (R.) – Heterocycles as key substrates in multicomponent reactions: the fast lane toward molecular complexity. Chem. Eur. J., 14, p. 8444-8454 (2008).
ULACZYK-LESANLO (A.) and HALL (D.G.) – New multicomponent reactions for generating libraries of polycyclic natural products. Curr. Opin. Chem. Biol. 9, pp. 266-276 (2005).
GANEM (B.) – Strategies for...
The Ultimate Scientific and Technical Reference
