Article | REF: NM4200 V1

Creation of nano-object-recognizing biomolecules through directed evolution

Authors: Philippe MINARD, Michel DESMADRIL

Publication date: April 10, 2007 | Lire en français

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    1. Proteins: the molecular actors of life

    Philippe Minard is Professor at the University of Paris Sud (Orsay).

    Michel Desmadril is CNRS Research Director

    Both are members of the Protein Modeling and Engineering Team, IBBMC, UMR 8619 Université Paris Sud, CNRS.

    Proteins are abundant in all organisms and, in fact, are essential constituents of life. They have a very wide range of functions. Perhaps one of the best known is their ability to catalyze chemical reactions: most chemical reactions that take place in a biological system are catalyzed by enzymes, which are proteins. Catalyzed reactions may involve very simple systems, such as the hydration of carbon dioxide, or chemical modifications of small organic molecules, or even complex transformations of macromolecules, or reactions involving mechanical work. Enzymes...

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