6. Functionalization of gold nanoparticles: an effective strategy for complementary properties
In addition to the properties specific to the gold element and gold nanoparticles, additional and complementary functions can be provided by ligands. Gold nanoparticles can be functionalized during synthesis (Brust method) or after synthesis (post-functionalization) by replacing citrate ions (gold nanoparticles obtained by the Turkevitch or Frens method) or part of the ligands supplied during synthesis.
6.1 Active targeting
Eradicating solid tumors by exploiting the properties of nanoparticles requires their preferential accumulation in the tumor. While this preferential accumulation is made possible by passive targeting (EPR effect), it can be enhanced by prolonging the duration of residence in the tumor. To achieve this, nanoparticles can be functionalized...
The Ultimate Scientific and Technical Reference
This article is included in
Nanosciences and nanotechnologies
This offer includes:
Knowledge Base
Updated and enriched with articles validated by our scientific committees
Services
A set of exclusive tools to complement the resources
Practical Path
Operational and didactic, to guarantee the acquisition of transversal skills
Doc & Quiz
Interactive articles with quizzes, for constructive reading
Functionalization of gold nanoparticles: an effective strategy for complementary properties
Image-guided therapy
Bibliography
Websites
Or-Nano, CNRS Research Group (GdR CNRS 2986) [On line].
http://www.insp.upmc.fr/webornano/
(page consulted on May 5, 2014)
CNRS, Sagascience, Nanotechnology & health [Online]
...Events
Noble Metal Nanoparticles Conference is held every two years.
http://www.grc.org/programs.aspx?year=2014&program=noblemetal
Nanohybrides conference is held every year.
Colloidal Nanoparticles for Biomedical Applications conference is held every year.
...Regulations
Decree no. 2012-232 of February 17, 2012 on the annual declaration of substances in nanoparticulate form.
Directory
Manufacturers – Suppliers – Distributors (non-exhaustive list)
Nano-H, Saint Quentin Fallavier
Nanoprobes Inc, Yaphank, NY 11980-9710, USA
Organizations – Federations – Associations...
The Ultimate Scientific and Technical Reference
