1. Preparation of polyfunctionalized organometallic species
An organometallic compound has a more or less polarized carbon-metal bond. The more ionic the carbon-metal bond, the more reactive it is to electrophiles (E + ). On the other hand, the more covalent the carbon-metal bond, the more inert it will be to electrophiles, and consequently the more functional groups are tolerated in these organometallic species.
In practice, C-Mg and especially C-Zn bonds are compatible with a large number of functional groups, and efficient and general synthesis methods have been developed since the late 80s.
The Ultimate Scientific and Technical Reference
This article is included in
Unit operations. Chemical reaction engineering
This offer includes:
Knowledge Base
Updated and enriched with articles validated by our scientific committees
Services
A set of exclusive tools to complement the resources
Practical Path
Operational and didactic, to guarantee the acquisition of transversal skills
Doc & Quiz
Interactive articles with quizzes, for constructive reading
Preparation of polyfunctionalized organometallic species
Continuous flow organometallic reactions
Bibliography
The Ultimate Scientific and Technical Reference
