Catalytic Appel reaction
Phosphine redox catalysis
Research and innovation REF: IN405 V1
Catalytic Appel reaction
Phosphine redox catalysis

Authors : Charlotte LORTON, Arnaud VOITURiEZ

Publication date: March 10, 2021 | Lire en français

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6. Catalytic Appel reaction

6.1 Introduction to Call Reaction

Another nucleophilic substitution reaction promoted by phosphines is the Appel reaction . In this transformation, alcohols (R 3 C-OH) are converted to alkyl halides (R 3 C-X), using a stoichiometric amount of triphenylphosphine. This reaction...

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