Polymorphism and solid phase transitions in solution
Polymorphism and solid phase transition in solution
Article REF: J2160 V1
Polymorphism and solid phase transitions in solution
Polymorphism and solid phase transition in solution

Authors : Denis MANGIN, François PUEL, Stéphane VEESLER

Publication date: March 10, 2008 | Lire en français

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3. Polymorphism and solid phase transitions in solution

3.1 Solubility curves

As a first step, let's consider a system with two polymorphic varieties I and II, polymorph II being more stable than polymorph I. The more stable has the lower free enthalpy:

GII<GI( 4 )

At equilibrium, polymorph i (i = I or II) is in contact with its saturated solution. The free enthalpies or chemical potentials are identical for each species in the solid and liquid phases, and becomes :

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