How do you establish a DNEL?
Determining DNELs
Practical sheet REF: FIC1182 V1
How do you establish a DNEL?
Determining DNELs

Author : Alain LOMBARD

Publication date: February 10, 2015, Review date: September 1, 2025 | Lire en français

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2. How do you establish a DNEL?

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First of all, the toxicological profile of the substance must be established and all relevant data collected. The most relevant and valid studies should then be selected (Klimisch, see Criteria for determining the rating of a study (Tool Criteria for determining the rating of a study. Adapted from Klimisch et al (1997) and Rosner (1994) )).

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