1. What is a CMR (carcinogenic, mutagenic, reprotoxic) agent?

A carcinogen is a substance or mixture that can cause cancer or increase its incidence.

A mutagen is a substance or mixture that can produce hereditary genetic defects or increase their frequency.

A reproductive toxicant is a substance or mixture that may produce or increase the frequency of non-heritable adverse effects in the offspring, or impair reproductive functions or capacity.

There are three categories of CMRs in the CLP Regulation EC No. 1272/2008:

• category 1 A: substances and preparations known to be CMR for humans ;

• category 1 B: substances and preparations for which there is a strong presumption that exposure to humans may produce CMR effects or increase their frequency;

• category 2: substances...