Flow synthesis of active pharmaceutical ingredients
Microfluidics, a versatile tool in healthcare
Article REF: PHA1030 V1
Flow synthesis of active pharmaceutical ingredients
Microfluidics, a versatile tool in healthcare

Authors : Jérémie GOUYON, Thibault ROQUES-CARMES, Anne SAPIN-MINET, Marianne PARENT

Publication date: October 10, 2024 | Lire en français

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3. Flow synthesis of active pharmaceutical ingredients

3.1 Summary

The synthesis of active pharmaceutical ingredients (APIs) has traditionally been carried out on a large scale (up to 100 t for certain products) using a batch synthesis method. Microfluidics – here embodied by the use of microreactors – enables the switch to a flow synthesis method, notably improving enantioselectivity and limiting the formation of by-products ...

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