Therapeutic target identification and validation: the case of enzymes
Microfluidics, a versatile tool in healthcare
Article REF: PHA1030 V1
Therapeutic target identification and validation: the case of enzymes
Microfluidics, a versatile tool in healthcare

Authors : Jérémie GOUYON, Thibault ROQUES-CARMES, Anne SAPIN-MINET, Marianne PARENT

Publication date: October 10, 2024 | Lire en français

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1. Therapeutic target identification and validation: the case of enzymes

In the therapeutic discovery phase, thousands of candidate molecules are analyzed to test their efficacy against a given target (drug screening). Of these, only several hundred will be retained for further preclinical development (optimization of synthesis, formulation (§ 3 and

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